Tracer metabolomics
Understanding metabolic fluxes is essential for uncovering biochemical mechanisms behind diseases, drug responses, and genetic variations. Tracer metabolomics offers a unique window into these dynamic processes by tracking labeled substrates through metabolic pathways. However, interpreting tracer metabolomics data is technically challenging, as it requires the integrated analysis of metabolite levels, isotopic tracer incorporation patterns, and their specific localization within metabolic pathways.
In this three-day course, you will build a solid foundation in tracer metabolomics. You will learn the key principles, how to design an experiment, and how to interpret analysis results with confidence.
Learning outcomes
- Explain the core principles and concepts of tracer metabolomics and its role in studying metabolic fluxes
- Plan and design tracer metabolomics experiments with best practices in mind
- Prepare samples according to high-quality standards for tracer-based studies
- Get insights into computational tools employed by the Metabolomics Core to analyze tracer metabolomics
- Interpret and evaluate the results of tracer metabolomics analyses generated by the Metabolomics Core
Approach
This training combines lectures with demo sessions to provide both theoretical and practical background in tracer metabolomics. A guided tour of the Metabolomics Core facility will offer insights into technologies and workflows used in real-world applications, including hands-on sample preparation in the lab.
Participants are expected to bring their own laptops to actively participate in the practical components.
Required skills
Please note that this training will be followed by a training session dedicated to spatial metabolomics.
If you want to attend the spatial metabolomics training, you also have to attend this one.
Extra information
This course is part of the learning path Spatial metabolomics data.